Marengo CIMS successfully treats a 61-Year-Old Woman with one of the rarest blood disorders,
Thrombotic Thrombocytopenic Purpura (TTP) with Advanced Medical Care
TTP is a rare and life-threatening blood disorder that affects 1 in 10 lakh people globally
The patient was brought in a critical condition with multiple organ dysfunction
Ahmedabad: Marengo CIMS Hospital once again establishes the highest level of clinical excellence in the team of doctors in treating a patient suffering from one of the rarest of blood disorders called Thrombotic Thrombocytopenic Purpura (TTP). Thrombotic Thrombocytopenic Purpura (TTP) is a rare and life-threatening blood disorder that affects approximately 1 in 10 lacs Globally. The team was led by Dr Kaumil Patel, Sr. Consultant, Department of Hematology, Marengo CIMS Hospital.
TTP, or Thrombotic Thrombocytopenic Purpura, is a rare blood disorder characterized by the formation of blood clots in small blood vessels throughout the body. These clots can lead to a reduction in platelet counts (thrombocytopenia), destruction of red blood cells (hemolytic anemia), and organ damage due to restricted blood flow. TTP is considered a medical emergency, and prompt treatment is essential to prevent severe complications or death. The primary treatment is plasma exchange therapy (plasmapheresis), which helps to remove the antibodies responsible for the disorder and replace them with healthy plasma.
The patient, Seema Devi, is a 61-year-old woman who was brought to the emergency at Marengo CIMS Hospital with critically low hemoglobin and platelet levels. She was presented to the doctors with severe fatigue, bruising, and symptoms indicating multiple organ dysfunctions. Preliminary tests, coupled with clinical acumen, quickly identified that she was suffering from TTP. During her hospitalization, the patient faced numerous complications as a result of TTP, affecting her lungs, kidneys, heart, and brain.
Dr. Kaumil Patel, the treating hematologist, and the dedicated ICU team, ensured each complication was expertly managed. The multidisciplinary approach was crucial in stabilizing her condition and preventing further deterioration. The only effective treatment for TTP, plasma exchange therapy (plasmapheresis), was initiated immediately. In this treatment, plasma is removed from the patient’s blood and replaced with healthy plasma. The collaborative efforts of specialists from various departments, including pulmonology, nephrology, cardiology, and neurology, played a pivotal role in her recovery.
The recovery of patients afflicted with TTOP is arduous, involving a prolonged hospitalization of 58 days. During this period, the patient has to undergo numerous plasma exchange sessions, intensive monitoring, and treatment for organ-specific complications. The medical team’s relentless efforts and the patient’s resilience are key factors in their recovery. On discharge, the patients are in excellent health, as this patient was, with stabilized hemoglobin and platelet levels, and no signs of organ dysfunction. Her remarkable recovery is a testament to the advanced medical care and the comprehensive, patient-centered approach adopted by Marengo CIMS Hospital.
Dr Kaumil Patel, Sr Consultant, Department of Hematology said, “Treating Thrombotic Thrombocytopenic Purpura is both challenging and rewarding. This condition, characterized by widespread microvascular clotting, can rapidly become life-threatening if not promptly addressed. Our primary treatment, plasma exchange therapy, is a critical intervention that can significantly reduce mortality and improve long-term outcomes. It works by removing the antibodies causing the disease and replacing them with healthy plasma, which helps to stop the destruction of platelets and red blood cells. While the treatment process is intensive and requires a multidisciplinary approach, the potential for full recovery makes it all the more imperative. Seeing a patient recover from TTP is one of the most gratifying experiences in Hematology.”
Dr Kaumil Patel emphasized the importance of early detection and prompt treatment initiation in managing blood disorders like TTP. “Recognizing suspicious symptoms early and starting treatment without delay is crucial in improving patient outcomes. The significance of a multidisciplinary approach is very crucial, and the collaborative efforts of various specialists are instrumental in managing the complexities of these cases and ensuring the best possible outcomes for the patients.”
Gaurav Rekhi, Regional Director, Marengo CIMS Hospitals said, “Marengo CIMS Hospital has emerged over the last few years as a healthcare provider to rely upon for optimized healthcare solutions for medical diseases and challenges of every sort. In recent times we have introduced techniques and technologies with a single-minded focus on ‘Patient First’. We are proud our doctors have been able to save this patient with one of the rarest blood disorders and we hope to continue on the path of treating every patient who invests trust and confidence in us.”
Thrombotic Thrombocytopenic Purpura (TTP) is a rare blood disorder, that affects between 6 to 10 people in every million. Another study reveals that Thrombotic thrombocytopenic purpura (TTP) is a rare and often fatal disorder with an estimated incidence of 3.7 cases per 1 million people (0.0004%). The current rate of occurrence for TTP is about 3.7 cases per million people each year. One estimate places the overall incidence rate at four of 100,000 individuals. Two-thirds of individuals with iTTP cases are women. The present study revealed that the prevalence rate of neonatal thrombocytopenia was 3.4% in various cities in India.
